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The projects constituting the SEURAT-1 research initiative have received funding from the European Union Seventh Framework Programme (FP7/2007-2013). The projects constituting the SEURAT-1 research initiative have received financing from Cosmetics Europe.

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CeeTox, Inc. Awarded ToxCastâ„¢ Contract by EPA

08/16/2011
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August 8, 2011 – Kalamazoo, Mich. – CeeTox, Inc., a Michigan life sciences company, announced today that it has been awarded a contract under the U.S. Environmental Protection Agency’s (EPA) ToxCast™ Program.

The contract has a maximum value of $25.9 million in year one with four additional one-year options bringing the total possible award to $129.6 million. It is for the testing of "High Throughput Complex Cell Co-Culture Systems" and will aid the EPA in prioritizing and testing thousands of compounds from "green" chemicals and food additives to industrial chemicals and chemicals used in cosmetics and consumer products.

CeeTox, founded in 2003, is a contract research organization (CRO) focused on in vitro toxicity and safety screening of new products including drug candidates, medical devices, cosmetics, personal care products, agricultural chemicals and household chemicals. In vitro typically refers to a test that is performed in a cell model instead of in or on an animal.

CeeTox was chosen through an open, competitive request-for-proposal process and awarded the contract based on excellence in four areas: technical proposal, qualifications of personnel, quality assurance / quality control program and past performance. "We are excited to be working with the EPA on this program. It will ultimately deliver better science at a lower cost, without the use of animals in testing," said Tim Mitchell, president of CeeTox.

CeeTox uses a systems-biology approach that evaluates the effect of test compounds on multiple biochemical processes over a wide range of exposures and times, making it possible to identify the most sensitive subcellular targets of toxicity.

One of the things that make CeeTox’s approach unique is the use of proprietary mathematical algorithms which help predict in vivo toxicities with a high degree of accuracy. "Our goal is to use cell based models to predict human toxicity," said Dr. James McKim, CeeTox chief scientific officer.

CeeTox will initially screen up to 1,000 chemicals. Those results will be combined with data already being generated by the other 500 rapid chemical tests used by the EPA’s ToxCast Program. The contract has the option of expanding to test 10,000 chemicals over the next five years.

The EPA’s goal is to provide additional information on the mechanisms of toxicity to the existing data sets. "We will employ the same exceptional science, technology and service we offer our clients to help EPA add to its body of knowledge," said Mitchell. "The ToxCast Program will ultimately help us better understand and mitigate the toxic effects of chemicals in our world," said Mitchell.

Contact: Mary Miller - Hart Associates

419-893-9600 x142 or 248-229-0175 mobile

mmiller[at]hartinc[dot]com

 

About CeeTox, Inc.

CeeTox, Inc., was founded in Kalamazoo, Michigan, in 2003 as a contract research organization focused on in vitro toxicity testing of new products including cosmetics, potential drug candidates and pesticides. CeeTox serves the pharmaceutical, medical device, personal care and chemical industries. CeeTox is headquartered at the Southwest Michigan Innovation Center in Western Michigan University’s Business Technology Research Park. For more information, please visit us at www.ceetox.com.

in vitro toxicity testing of new products including cosmetics, potential drug candidates and pesticides. CeeTox serves the pharmaceutical, medical device, personal care and chemical industries. CeeTox is headquartered at the Southwest Michigan Innovation Center in Western Michigan University’s Business Technology Research Park. For more information, please visit us at www.ceetox.com.

Last changed: 08/16/2011

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